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Health Services Research of Integrative Oncology in Palliative Care of Patients with Advanced Pancreatic Cancer
Background: Pancreatic cancer has a dire prognosis and is associated with a high mortality. Palliative patients have special needs and often seek help in integrative oncological concepts (IO) that combine conventional and complementary therapies. Nevertheless there...
The action of Hyperthermia in Metastatic Colorectal Cancer in Combination with Chemotherapy
Abstract Background: Colorectal cancer (CRC) is the second leading cause of death in adults. Standard treatment for metastatic disease includes chemotherapy and biological agents. Although more than 50% of patients respond to multi agent chemotherapy, resistance to...
Vitamin C Enhances Tumor Inhibitory Effects of Gefitnib in Non Small Cell Lung Cancer
Abstract A persistent human papillomavirus (HPV) infection of a high-risk type is necessary for cervical cancer to develop. The severity of the diagnosis, together with colposcopy findings, determines the standard for treatment, and ablative or excisional options may...
Phase I Trial Shows Safety and Tolerability of Intravenous Mistletoe Extract in Patients with Advanced Solid Tumors
A Phase I clinical trial evaluated the safety and tolerability of intravenous mistletoe extract in patients with advanced solid tumors. Mistletoe extract has been used as a complementary therapy in cancer treatment, and this study aimed to determine the maximum...
High Dose Vitamin C in Metastatic Lung Cancer and Glioblastoma Multiforme
Highlights High-dose ascorbate sensitizes NSCLC and GBM cells to radio-chemotherapy O2⋅− and H2O2 increase labile iron causing cancer cell-selective ascorbate toxicity Therapeutic levels of ascorbate are achievable and well tolerated in GBM and NSCLC Cancer...
Prospective Phase II trial of Regional Hyperthermia and Whole Liver Irradiation for Numerous Chemorefractory Liver Metastases from Colorectal Cancer
Prospective phase II trial of regional hyperthermia and whole liver irradiation for numerous chemorefractory liver metastases from colorectal cancer. Purpose: A prospective phase II trial was conducted to evaluate the effectiveness and toxicity of regional...
Targeted Photodynamic Therapy as Potential Treatment Modality for the Eradication of Colon Cancer and Colon Cancer Stem Cells
Targeted photodynamic therapy as potential treatment modality for the eradication of colon cancer and colon cancer stem cells Abstract Colorectal cancer is commonly treated by tumour resection, as chemotherapy and radiation have proven to be less effective, especially...
Escharotic Treatment for Cervical Dysplasia – Case Report
AbstractA persistent human papillomavirus (HPV) infection of a high-risk type is necessary for cervical cancer to develop. The severity of the diagnosis, together with colposcopy findings, determines the standard for treatment, and ablative or excisional options may...
AML and IVC + Chemo Study
SUMMARY OF RESULTS The complete response rate was 79.92% vs. 44.11%; P = 0.004 in favor of the IVC + chemo group. The median survival was close to double in the IVC + chemo group 15.3 months vs.. 9.3 months, P = 0.039. Leuk Res. 2018 Mar;66:1-7. The synergy of Vitamin...
Photodynamic Therapy for Carcinoma In Situ of the Anus
Hypothesis Photodynamic therapy (PDT) for carcinoma in situ of the anus is an alternative to surgical excision in patients who are seropositive for human immunodeficiency virus (HIV).Design Before-after trial. Settings Tertiary referral center. Patients Twelve...
Study on Relapsed Malignant Gliomas Treated with Electro-Hyperthermia
Aim: to evaluate the efficacy and tolerability of electro-hyperthermia (ET) for the treatment of relapsed malignant glioma. Methods: this was a retrospective observational clinical study. Patients were included in the study if they had >18 years, informed...
Evidence for Loco-Regional Moderate Hyperthermia in the Adjunct Management of Cancers
A Phase I clinical trial evaluated the safety and tolerability of intravenous mistletoe extract in patients with advanced solid tumors. Mistletoe extract has been used as a complementary therapy in cancer treatment, and this study aimed to determine the maximum...
A Review of the Current Clinical Evidence for Loco-Regional Moderate Hyperthermia in the Adjunct Management of Cancers
A study published in January 2023 addresses the limited knowledge in the field of oncology regarding the use of moderate hyperthermia in cancer management. The review summarizes clinical data on the application of loco-regional and superficial hyperthermia as an...
The Utility of Hyperthermia for Local Recurrence of Breast Cancer
Background: Hyperthermia has long been used in combination with chemotherapy or radiation therapy for the treatment of superficial malignancies, in part due to its sensitizing capabilities. Patients who suffer from superficial recurrences of breast cancer have poor...
Response of Breast Cancer Cells and Cancer Stem Cells to Metformin and Hyperthermia Alone or Combined
Metformin, the most widely prescribed drug for treatment of type 2 diabetes, has been shown to exert significant anticancer effects. Hyperthermia has been known to kill cancer cells and enhance the efficacy of various anti-cancer drugs and radiotherapy. We...
Local Control Rate After the Combination of Re-Irradiation and Hyperthermia for Irresectable Recurrent Breast Cancer: Results in 248 Patients
Background and purpose: Randomized studies have shown that adding hyperthermia (HT) to re-irradiation (re-RT) improves treatment outcome for patients with breast cancer recurrences. We evaluated the efficacy and side effects in patients treated with re-RT and HT for...
Hyperthermia and Reirradiation for Locoregional Recurrences in Preirradiated Breast Cancers: A Single Institutional Experience
QUESTIONS UNDER STUDY: The aim of this retrospective analysis was to evaluate the safety and efficacy of local hyperthermia (HT) and reirradiation (ReRT) in the management of preirradiated locoregional recurrent breast cancers at Kantonsspital Aarau, Switzerland....
Hyperthermia for Locally Advanced Breast Cancer
Hyperthermia (HT) has a proven benefit for treating superficial malignancies, particularly chest wall recurrences of breast cancer. There has been less research utilising HT in patients with locally advanced breast cancer (LABC), but available data are promising. HT...
