Escharotic treatment for cervical dysplasia - case report

Escharotic treatment for cervical dysplasia – case report

Escharotic treatment for cervical dysplasia – case report:



A persistent human papillomavirus (HPV) infection of
a high-risk type is necessary for cervical cancer to
develop. The severity of the diagnosis, together with
colposcopy findings, determines the standard for
treatment, and ablative or excisional options may be
recommended. Escharotic treatment, together with an
oral, anticarcinogenic HPV protocol and a vaginalsuppository
protocol, is an alternative treatment,
especially for those women of childbearing age who are
concerned about the possibility of obstetrical
complications associated with the use of loop
electrosurgical excision (LEEP). The aim of the current
case study was to observe the effect of an ablative
escharotic treatment for a woman with severe dysplasia,
cervical intraepithelial neoplasia grade 3 (CIN3). A
28-y-old female visited the National College of Natural
Medicine clinic to obtain suggestions for alternative
treatments following a satisfactory colposcopy and a
biopsy revealing a high-risk HPV effect, severe dysplasia
CIN3, and a positive endocervical curettage (ECC). She
refused the recommended standard of care, a LEEP,
because of concerns about the potential for future
obstetrical complications. As an alternative, she elected
to receive an escharotic treatment at a frequency of 2
treatments/wk for 5 wk. In addition to the escharotic
treatment, she followed an oral protocol consisting of
vitamins and botanical medicine for 1 y and she
completed a 12-wk regime of vaginal suppositories
following the escharotic. The authors followed her for 2
y. The woman’s Papanicolaou (Pap) test at the 6-mo
follow-up revealed negative cervical cytology for
intraepithelial lesion or malignancy, and her follow-up
ECC was negative. Liquid-based Pap results were
normal, and HPV testing was negative at her 1-y followup.
Her Pap continued to remain normal at her 2-y
follow-up. For women with high-grade cervical
neoplasias and positive ECCs, with satisfactory
colposcopies, escharotic treatment, accompanied by
oral supplementation, holds promise as an effective
alternative to LEEP and other excisional procedures.