The action of hyperthermia in metastatic colorectal cancer in combination with chemotherapy

The action of hyperthermia in metastatic colorectal cancer in combination with chemotherapy

Latest update in The action of hyperthermia in metastatic colorectal cancer in combination with chemotherapy

 

ABSTRACT
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Introduction: Hyperthermia is characterized as the
fourth pillar in treating cancer, including surgery,
chemotherapy and radiation. Clinical studies
suggest that the combination of hyperthermia with
radiation and chemotherapy, can bring very good
results in treating various types of cancer, including
colon cancer.
Purpose: To investigate the effects of hyperthermia
in metastatic colorectal cancer in combination with
chemotherapy.
Materials and methods: A clinical study, which
recruited 32 patients with diagnosed colorectal
cancer. The patients were divided into a reference
group (15 patients), which received chemotherapy
and sessions of hyperthermia and in a control group
(17 patients), which only received chemotherapy.
For the application of hyperthermia, the Celsius
42+ machine was used. Imaging tests were
performed before and after taking the regimens, in
order to evaluate the effectiveness of each treatment
approach.
Results: Through the imaging assessment, a
positive outcome of the disease was observed, for
the team of hyperthermia (reference group).
Specifically, when compared with the control
group, the reference group showed a shrinkage of
metastatic foci, derived from colon cancer. In
contrast, in the control group there was an increase
of dimensions compared with hepatic metastases
and metastases in the abdomen, while a steady state
was maintained regarding thoracic metastases.
Conclusions: The beneficial effects of hyperthermia
are undeniable, as year after year resulting
more and more clinical trial data that support this
view. The consolidation of the application of
hyperthermia cancer treatment, is now a matter of
time.
Key words: colon cancer, colorectal cancer,
treatment, hyperthermia, oncothermia, chemotherapy,
supplementary therapy