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The western diet many of us have become accustomed to is behind a rise in low-grade intestinal inflammation and immune-mediated inflammatory diseases, and while research has focused on anti-inflammatory properties of isolated compounds it has yet to focus largely on the underlying mechanisms at play.

A newly published study looked at the complex relationship between habitual diet, gut microbiota and intestinal inflammation in humans. The study looked at 173 dietary factors ranging from dietary patterns to specific foods and micro nutrients. The study, completed in the Netherlands, included 1425 individuals from four cohorts: Crohn’s disease, ulcerative colitis, IBS, and the general population.

Each participant had stool collected, with DNA extracted and sequenced, and the results showed across the board through all cohorts that habitual diet played a key roll in inflammation and gut microbial changes. Diets high in legumes, vegetables, fruits and nuts, which had a higher intake of plant based foods over animal sources and a preference for low-fat fermented dairy and fish, while avoiding strong alcohol, high fat meats and soft drinks has a potential to prevent intestinal inflammatory processes.

Source: Medscape

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